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According to in vitro studies, SFN affects the Th17 lymphocyte population by inhibiting the transcription factor RORγt, which reduces the production of IL-17—one of the key cytokines driving the inflammatory process in RA
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[DOI] [PubMed] [Google Scholar] 49.Ilic S, Drmic D, Zarkovic K, Kolenc D, Coric M, Brcic L, Klicek R, Radic B, Sever M, Djuzel V, Ivica M, Boban Blagaic A, Zoricic Z, Anic T, Zoricic I, Djidic S, Romic Z, Seiwerth S, Sikiric P