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It provided a novel clinical antitumor therapeutic strategy to induce ferroptosis via the consumption of GSH, disrupt redox balance by the Fenton reaction and doxorubicin-supplied hydrogen peroxide, synergistic cytotoxicity of doxorubicin inhibition of recurrence and metastasis of HCC, and reversing drug resistance in translational therapy
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Certain flavonoids can even promote neuronal recovery: fisetin, quercetin, luteolin, and others have been observed to induce neurite outgrowth and synaptic marker expression, suggesting a capacity to support neural regeneration, although this requires continuous presence of the compounds and appears dose-dependent (9)